Unique Plan Description: InFLIXimab (Remicade/Inflectra) administration
Plan Selection Display: InFLIXimab (Remicade/Inflectra) administration
PlanType: Medical                                 
Version: 1          
Begin Effective Date: 2021-09-16 06:15:00
End Effective Date: 2100-12-31 00:00:00
Last Updated Date: 2021-12-20 11:02:10
Available at all facilities: Yes

InFLIXimab (Remicade/Inflectra) administration
Medications
		inFLIXimab 5 mg/kg dosage:(NOTE)*
	Remicade/NS
		5 mg/kg, EVERY BAG
		250 mL, IV, Routine, T;N, 8 hr, 10 ml/hr
			Comment: 5 mg/kg Infuse over a period of at least 2 hours.IV infusions may be given at a rate of 2 mL/minute or, alternatively, a rate titration schedule may be used in an attempt to prevent or ameliorate acute infusion reactions.A rate titration schedule can be used in patients receiving an initial infliximab dose, those without a history of acute infusion reactions, and those with a history of such reactions.Rate Titration ScheduleRate                         Time10 mL/hour         first 15 minutes20 mL/hour         next 15 minutes40 mL/hour         next 15 minutes80 mL/hour         next 15 minutes150 mL/hour      next 30 minutes250 mL/hour      next 30 minutesTarget Dose: inFLIXimab 5 mg/kg
	Inflectra/NS
		250 mL, IV, Routine, T;N, 8 hr, 10 ml/hr
			Comment: 5 mg/kg Infuse over a period of at least 2 hours.IV infusions may be given at a rate of 2 mL/minute or, alternatively, a rate titration schedule may be used in an attempt to prevent or ameliorate acute infusion reactions.A rate titration schedule can be used in patients receiving an initial infliximab dose, those without a history of acute infusion reactions, and those with a history of such reactions.Rate Titration ScheduleRate                         Time10 mL/hour         first 15 minutes20 mL/hour         next 15 minutes40 mL/hour         next 15 minutes80 mL/hour         next 15 minutes150 mL/hour      next 30 minutes250 mL/hour      next 30 minutesTarget Dose: inFLIXimab 5 mg/kg
		5 mg/kg, EVERY BAG
		inFLIXimab 10 mg/kg dosage:(NOTE)*
	Remicade/NS
		250 mL, IV, Routine, T;N, 8 hr, 10 ml/hr
			Comment: 10 mg/kg Infuse over a period of at least 2 hours.IV infusions may be given at a rate of 2 mL/minute or, alternatively, a rate titration schedule may be used in an attempt to prevent or ameliorate acute infusion reactions.A rate titration schedule can be used in patients receiving an initial infliximab dose, those without a history of acute infusion reactions, and those with a history of such reactions.Rate Titration ScheduleRate                         Time10 mL/hour         first 15 minutes20 mL/hour         next 15 minutes40 mL/hour         next 15 minutes80 mL/hour         next 15 minutes150 mL/hour      next 30 minutes250 mL/hour      next 30 minutesTarget Dose: inFLIXimab 10 mg/kg
		10 mg/kg, EVERY BAG
	Inflectra/NS
		250 mL, IV, Routine, T;N, 8 hr, 10 ml/hr
			Comment: 10 mg/kg Infuse over a period of at least 2 hours.IV infusions may be given at a rate of 2 mL/minute or, alternatively, a rate titration schedule may be used in an attempt to prevent or ameliorate acute infusion reactions.A rate titration schedule can be used in patients receiving an initial infliximab dose, those without a history of acute infusion reactions, and those with a history of such reactions.Rate Titration ScheduleRate                         Time10 mL/hour         first 15 minutes20 mL/hour         next 15 minutes40 mL/hour         next 15 minutes80 mL/hour         next 15 minutes150 mL/hour      next 30 minutes250 mL/hour      next 30 minutesTarget Dose: inFLIXimab 10 mg/kg
		10 mg/kg, EVERY BAG
	Tylenol
		650 mg, Tab, By Mouth, Once, T;N
			Comment: prior to infusion
	Benadryl
		25 mg, Capsule, By Mouth, Once
			Comment: prior to infusion
	SOLU-Medrol
		80 mg, Injection, IV Push, Once
			Comment: prior to infusion
	cyanocobalamin
		1,000 mcg, Injection, IM-Intramuscular, Once
Patient Care
	Vital Signs
		Prior to initiation of infusion and assess for any signs/symptoms of current infection, and every 30 minutes until infusion complete.  If clinically significant changes in vital signs occur, stop the infusion and notify M
	Notify MD
		Any abnormal baseline vital signs or Symptoms of moderate to severe reaction or severe hypersensitivity.
		T;N, Contact Provider for further orders if allergic reaction protocol initiated.
	Initiate MD Plan for:
		T;N, Allergy Reaction protocol if patient experiences reaction to treatment.

*Report Legend:
DEF - This order sentence is the default for the selected order
GOAL - This component is a goal
IND - This component is an indicator
INT - This component is an intervention
IVS - This component is an IV Set
NOTE - This component is a note
Rx - This component is a prescription
SUB - This component is a sub phase